Author

J.-H. Ko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

J. Behmoaras· 3 shared M. Pereira· 2 shared A. E. Papathanassiu· 1 shared A. Guerrero· 1 shared A. L. M. Tan· 1 shared A. Olona· 1 shared B. B. Manshian· 1 shared C. D. Rose· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCell Biology

J. Behmoaras

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BCAT1 inhibition affects CD8+ T cell activation, exhaustion, and tumoral immunity by altering iron homeostasis

F. Lodi, M. Certo, H. Elkafrawy, W. Li, H. A. Vu, K. Gilbo, L. Su, I. L. Pegg, T. Weiss, M. Bühler, M. Weller, C. Yeh, J. E. Corn, K.-S. E. Park, J.-H. Ko, , A. E. Papathanassiu

This study shows BCAT1 inhibition alters iron homeostasis, affecting CD8+ T cell activation, exhaustion, and tumor immunity, with potential as a cancer therapy.

bioRxiv · Feb 25, 2023 · PreprintImmunology

Multinucleation resets human macrophages for specialized functions at the expense of mononuclear phagocyte identity

K. Ahmadzadeh, M. Pereira, M. Vanoppen, E. Bernaerts, J.-H. Ko, T. Mitera, C. Maksoudian, B. B. Manshian, S. Soenen, C. D. Rose, P. Matthys, C. Wouters, J. Behmoaras

This study shows that multinucleation in human macrophages reduces mononuclear phagocyte identity and enables specialized functions in multinucleated giant cells.

bioRxiv · Aug 22, 2022Cell Biology

Cardiac glycosides cause selective cytotoxicity in human macrophages and ameliorate white adipose tissue homeostasis

A. Olona, C. Hateley, A. Guerrero, J.-H. Ko, M. Johnson, D. Thomas, J. Gil, J. R. Behmoaras

This study shows cardiac glycosides induce cytotoxicity in human macrophages and improve white adipose tissue homeostasis in obese patients.

bioRxiv · Sep 18, 2020Immunology

A trans-eQTL network regulates osteoclast multinucleation and bone mass

M. Pereira, J.-H. Ko, J. Logan, H. Protheroe, K.-B. Kim, A. L. M. Tan, K.-S. Park, M. Rotival, E. Petretto, J. H. D. Bassett, G. R. Williams, J. Behmoaras

The paper identifies a trans-eQTL network (MMnet) that regulates osteoclast multinucleation and bone mass in mice and humans.

bioRxiv · Feb 13, 2020Cell Biology