Author

N. Roda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

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Organism:human· 4 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1

Frequent Co-Authors

P. G. Pelicci· 3 shared A. Cossa· 2 shared A. Polazzi· 2 shared C. Priami· 2 shared L. Mazzarella· 2 shared V. Gambino· 2 shared A. Antoranz· 1 shared A. Bassez· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

P. G. Pelicci

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4 papers

Recent·Most cited

NK cells contribute to resistance to anti-PD1 therapy in immune-excluded melanomas

E. Landeloos, J. Pozniak, N. Roda, A. de Visscher, A. Antoranz, Y. van Herck, G. Bervoets, F. M. Bosisio, V. Boecxstaens, A. Bassez, D. Lambrechts, P. Matthys, O. Bechter, J.-C. Marine

The paper identifies NK cells as contributors to resistance to anti-PD1 therapy in immune-excluded melanomas using single-cell RNA sequencing and spatial proteomics.

bioRxiv · Dec 14, 2023 · PreprintCancer Biology

NF1 modulates microtubule repair and sensitivity to antibody-drug conjugates

B. Achutti Duso, E. Messuti, G. Tini, E. Bonetti, A. Castiglioni, G. Frige, G. Ciossani, S. Monzani, C. Soriani, D. Khuntsariya, N. Roda, A. Polazzi, M. R. Ippolito, E. Gavilan Dorronzoro, E. Mane, , L. Mazzarella

This study shows that NF1 loss increases sensitivity to the ADC T-DM1 by modulating microtubule repair and dynamics, identifying NF1 as a predictive biomarker for ADC response.

bioRxiv · Dec 6, 2023 · PreprintCancer Biology

INDOCYANINE GREEN IMAGING BY VITAL TISSUE SLICES SCANNING ALLOWS FOR THE ISOLATION OF INTACT LIVER MICRO-METASTASIS FOR SINGLE-CELL ANALYSIS

N. Roda, M. Stendardo, V. Gambino, G. Persico, A. Cossa, S. Rodighiero, C. Priami, N. Kaludercic, P. G. Pelicci, M. Giorgio

This study uses ICG imaging to isolate liver micro-metastases for single-cell analysis, revealing gene expression patterns predictive of breast cancer prognosis and therapeutic targets.

bioRxiv · Jun 21, 2023 · PreprintCancer Biology

The breast cancer pro-metastatic phenotype requires concomitant hyper-activation of ECM remodeling and dsRNA-IFN1 signaling in rare clone cells

N. Roda, A. Cossa, R. Hillje, A. Tirelli, F. Ruscitto, S. Cheloni, C. Priami, A. Dalmasso, V. Gambino, G. Blandano, A. Polazzi, P. Falvo, E. Gatti, L. Mazzarella, L. Luzi, , P. G. Pelicci

This study identifies that the breast cancer pro-metastatic phenotype arises from rare clones with hyper-activation of ECM remodeling and dsRNA-IFN1 signaling, and shows these genes predict metastasis progression.

bioRxiv · Jul 13, 2022Cancer Biology