Author

P. Mitchell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Ecology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

C. M. Thompson· 2 shared T. Azarian· 2 shared A. Callendrello· 1 shared A. Ghoulia· 1 shared A. J. Pollard· 1 shared A. Skoczynska· 1 shared A. von Gottberg· 1 shared B. A. Kwambana-Adams· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersEvolutionary Biology

C. M. Thompson

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Author profile →

5 papers

Recent·Most cited

A human-specific motif facilitates CARD8 inflammasome activation after HIV-1 infection

J. Kulsuptrakul, E. Turcotte, M. Emerman, P. Mitchell

The paper identifies a human-specific CARD8 motif that is cleaved by HIV-1 protease, leading to inflammasome activation and pyroptosis after HIV-1 infection.

bioRxiv · Oct 4, 2022Microbiology

Listeria monocytogenes personalized cancer vaccines drive therapeutic immune responses to cancer derived neoantigens

B. Coder, O. Pryshchep, D. Kelkar, E. Filippova, X. Ju, D. Balli, C. Mottershead, K. Ramos, N. Thambi, Z. Cheng, B. Vander Lugt, J. Lesch, X. Liu, J. DeVoss, K. Cooke, , M. Princiotta

This study demonstrates that ADXS-NEO, a personalized Listeria monocytogenes vaccine, effectively targets tumor-specific mutations and controls tumor growth in mice by inducing neoantigen-specific T cell responses.

bioRxiv · May 11, 2020 · PreprintImmunology

An agent-based model of insect resistance management and mitigation for Bt maize: A social science perspective

Y. Saikai, P. Mitchell, T. Hurley

This paper develops an agent-based model to study pest resistance to Bt maize, showing that social factors like networks influence resistance emergence and that refuge requirements are most effective for long-term mitigation.

bioRxiv · Aug 12, 2019Ecology

Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci

T. Azarian, P. Mitchell, M. Georgieva, C. M. Thompson, A. Ghoulia, A. J. Pollard, A. von Gottberg, M. du Plessis, M. Antonio, B. A. Kwambana-Adams, S. C. Clarke, D. Everett, J. Cornick, E. Sadowy, W. Hryniewicz, , W. P. Hanage

This study analyzes global serotype 3 pneumococcal isolates to show a recent emergence of Clade II with antibiotic resistance and antigenic diversity, not linked to PCV13 usage.

bioRxiv · Jun 27, 2018Evolutionary Biology

Population genomics of pneumococcal carriage in Massachusetts children following PCV-13 introduction

P. Mitchell, T. Azarian, N. J. Croucher, A. Callendrello, C. M. Thompson, S. I. Pelton, M. Lipsitch, W. Hanage

This study examines changes in pneumococcal carriage diversity and lineage distribution in Massachusetts children after PCV-13 introduction, finding increased diversity post-vaccination followed by a return to pre-vaccination levels.

bioRxiv · Dec 16, 2017Evolutionary Biology