CRTC2 regulates plasma cell metabolism and survival
J. Hong, F. Ahsan, E. Montecino-Rodriguez, P. Pioli, M.-s. Lee, T. Nguyen, D. Brooks, J. Golovato, K. Niazi, K. Dorshkind, M. Teitell
This study shows that CRTC2 repression is essential for plasma cell metabolism and survival, affecting antibody production and immune response durability.
bioRxiv · Apr 14, 2021 · PreprintImmunology