Author

D. Brooks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Ecology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Brito· 1 shared A. Clark· 1 shared A. Freund· 1 shared A. Highlands· 1 shared A. McCubbin· 1 shared A. McDevitt· 1 shared B. Bertol· 1 shared B. Moraes· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Brito

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Molecular, metabolic and functional CD4 T cell paralysis impedes tumor control

M. Guo, D. Abd-Rabbo, B. Bertol, M. Carew, S. Lukhele, L. Snell, W. Xu, G. Boukhaled, H. Elsaesser, M. J. Halaby, N. Hirano, T. McGaha, D. Brooks

This study identifies mechanisms by which CD4 T cell paralysis impairs tumor control by stalling proliferation and differentiation through Treg and CTLA4 signaling interactions.

bioRxiv · Apr 15, 2023 · PreprintCancer Biology

CRTC2 regulates plasma cell metabolism and survival

J. Hong, F. Ahsan, E. Montecino-Rodriguez, P. Pioli, M.-s. Lee, T. Nguyen, D. Brooks, J. Golovato, K. Niazi, K. Dorshkind, M. Teitell

This study shows that CRTC2 repression is essential for plasma cell metabolism and survival, affecting antibody production and immune response durability.

bioRxiv · Apr 14, 2021 · PreprintImmunology

Host-associated fungal communities are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome

X. A. Harrison, A. McDevitt, J. C. Dunn, S. Griffiths, C. Benvenuto, R. Birtles, J. P. Boubli, K. Bown, C. Bridson, D. Brooks, S. S. Browett, R. F. Carden, J. Chantrey, F. Clever, I. Coscia, , R. E. Antwis

The paper shows fungal communities in hosts are shaped by host phylogeny and interact with bacterial microbiomes across 49 species.

bioRxiv · Jul 7, 2020 · PreprintEcology

Pharmacological inhibition of longevity regulator PAPP-A restrains mesenchymal stromal cell activity

M. Mohrin, J. Liu, J. Zavala-Solorio, S. Bhargava, J. M. Trumble, A. Brito, D. Hu, D. Brooks, M. L. Bouxsein, R. Baron, Y. Kutskova, A. Freund

This study shows that inhibiting PAPP-A reduces collagen and ECM gene expression and modulates mesenchymal stromal cell activity in mice.

bioRxiv · Feb 5, 2020 · PreprintPhysiology

Polysaccharide-mediated synthesis of melanins from serotonin and other 5-hydroxy indoles

K. Vercruysse, A. Clark, N. Alatas, D. Brooks, N. Hamza, M. Whalen

The paper investigates polysaccharide-mediated oxidation of serotonin and 5-hydroxy indoles into melanin-like materials, showing one product affects cytokine release from immune cells.

bioRxiv · Sep 7, 2017Biochemistry