Author

P. R. Walker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Sundstrom· 1 shared c. brown· 1 shared C. Rancan· 1 shared D. Martinez Bedoya· 1 shared D. Migliorini· 1 shared E. D. Lu· 1 shared E. F. Simonds· 1 shared E. Marinari· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Sundstrom

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma

D. Martinez Bedoya, E. Marinari, S. Davanture, L. Castillo Cantero, S. Erraiss, M. Dockerill, S. Barluenga Badiola, N. Winssinger, K. Schaller, P. Bijlenga, S. Momjian, P. Hammel, P. Cosson, P. R. Walker, V. Dutoit, D. Migliorini

This study develops and validates anti-PTPRZ1 RNA CAR-T cells for glioblastoma treatment, showing antigen-specific and bystander antitumor activity in preclinical models.

bioRxiv · Dec 23, 2023Immunology

Deep immune profiling reveals targetable mechanisms of immune evasion in checkpoint blockade-refractory glioblastoma

E. F. Simonds, E. D. Lu, E. V. Liu, W. Tamaki, C. Rancan, J. Stultz, M. Sinha, L. K. McHenry, N. M. Nasholm, P. Chuntova, A. Sundstrom, V. Genoud, S. A. Shahani, L. D. Wang, c. brown, , M. Hellstrom

This study identifies immune evasion mechanisms in checkpoint blockade-refractory glioblastoma using deep immune profiling and shows that enhancing antigen presentation can improve immunotherapy response.

bioRxiv · Dec 1, 2020Cancer Biology