Author

P. Rochaix

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Bui· 1 shared C. Arenz· 1 shared C. Chevreau· 1 shared C. Leyrat· 1 shared C. M. Grison· 1 shared C. Merle· 1 shared D. Ranchere-Vince· 1 shared E. Darbo· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

B. Bui

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Author profile →

2 papers

Recent·Most cited

Distinct cellular origins and differentiation process account for distinct oncogenic and clinical behaviors of leiomyosarcomas

E. Darbo, G. Perot, L. Darmusey, S. Le Guellec, L. Leroy, L. Gaston, N. Desplat, N. Thebault, C. Merle, P. Rochaix, T. Valentin, G. Ferron, C. Chevreau, B. Bui, E. Stoeckle, , F. Chibon

The paper identifies a transcriptionally homogeneous subgroup of leiomyosarcomas originating from vascular smooth muscle cells and explains their unique oncogenic behavior through specific pathway alterations.

bioRxiv · Oct 23, 2020Cancer Biology

Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy

I. Vasiliauskaite - Brooks, R. D. Healey, P. Rochaix, R. Sounier, C. M. Grison, T. Waltrich - Augusto, M. Fortier, F. Hoh, E. M. Saied, C. Arenz, S. Basu, C. Leyrat, S. Granier

The paper reports the crystal structure of human ACER3, revealing its intramembrane architecture and explaining Ca2+ and Zn2+ regulation of its enzymatic activity and dysfunction in leukodystrophy.

bioRxiv · Jun 15, 2018Biochemistry