Cancer BiologybioRxiv
Distinct cellular origins and differentiation process account for distinct oncogenic and clinical behaviors of leiomyosarcomas
E. Darbo, G. Perot, L. Darmusey…·F. Chibon
The paper identifies a transcriptionally homogeneous subgroup of leiomyosarcomas originating from vascular smooth muscle cells and explains their unique oncogenic behavior through specific pathway alterations.
DOI 10.3390/cancers15020534