BioengineeringbioRxivPreprint
Tissue-engineered models of lung cancer premalignancy
R. Blomberg, K. Sompel, C. Hauer…·C. M. Magin
This paper develops a tissue-engineered model of human lung cancer premalignancy using hydrogel-embedded lung slices exposed to cigarette smoke carcinogens, showing the formation of premalignant lesions and testing chemoprevention agents.