P. J. Norman

This study compares human innate-like T cells (Tinn) with conventional T cells and mouse models, revealing distinct transcriptional programs and developmental pathways.

This study identifies KIR3DL3 expression in T cells, showing it is upregulated by unconventional stimulation and varies by individual genetic variants.

This paper develops PONG, a method to impute KIR3DL1/S1 alleles from whole-genome SNP data with high accuracy across populations, enabling large-scale genetic studies.

PING enables high-throughput, accurate KIR genotyping by addressing structural complexity and homology challenges in short-read sequencing data.

The paper shows that East Asian populations, particularly the Chinese Southern Han, have enhanced NK cell strength due to genetic admixture and natural selection of HLA class I alleles that interact with inhibitory KIR receptors.