Author

P. Searson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Liu· 1 shared B. A. Johns· 1 shared B. Smith· 1 shared I. Chiu· 1 shared J. Zhu· 1 shared L. Ruan· 1 shared M. Donowitz· 1 shared M. Zeineldin· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Liu

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1 paper

Recent·Most cited

Disruption of Epithelium Integrity by Inflammation-Associated Fibroblasts through Prostaglandin Signaling

Y. Dong, B. A. Johns, L. Ruan, M. Zeineldin, A. Liu, S. Raychaudhuri, I. Chiu, J. Zhu, B. Smith, N. Zhao, P. Searson, S. Watanabe, M. Donowitz, T. C. Larman, R. Li

This study shows inflammation-associated fibroblasts disrupt colon epithelial barrier integrity and genome stability via PGE2-EP4 signaling, and EP4 inhibitors can reverse these effects.

Science Advances · Apr 5, 2024Peer-reviewedCell Biology