Pharmacology & ToxicologybioRxivPreprint
Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts
DOI 10.1101/2023.01.27.525941
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J.-P. Alao, J. Johansson-Sjolander, C. Rallis, P. Sunnerhagen
This study shows caffeine stabilizes Wee1 via Rad24 but inhibits its accumulation during DNA damage, suggesting TORC1 mediates caffeine's effects on cell cycle progression.