ImmunologybioRxivPreprint
Mitochondrial oxidative stress drives IL-12/IL-18-induced IFN-gamma production by CD4+ T cells and is controlled by Fas
G. Rackov, P. T. Zaniani, S. C. del Pino…·D. Balomenos
This study shows that mitochondrial oxidative stress (mROS) is essential for IL-12/IL-18-induced IFN-gamma production in memory-like CD4+ T cells and is regulated by Fas, independent of apoptosis.
DOI 10.1101/2021.01.19.427239