Author

P. Tsichlis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. L. Bayer· 1 shared G. Laliotis· 1 shared H. Singh· 1 shared J. Pietruska· 1 shared K. L. PatrickiD· 1 shared K. O. West· 1 shared K. W. Lynch· 1 shared L. M. Agosto· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. L. Bayer

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2 papers

Recent·Most cited

AKT2 Loss Impairs BRAF-Mutant Melanoma Metastasis

S. K. McRee, A. L. Bayer, J. Pietruska, P. Tsichlis, P. W. Hinds

This study shows AKT2 promotes melanoma metastasis while AKT1 is critical for tumor initiation, suggesting AKT2 as a therapeutic target in BRAF-mutant melanoma.

bioRxiv · Aug 24, 2023 · PreprintCancer Biology

PRMT5 promotes symmetric dimethylation of RNA processing proteins and modulates activated T cell alternative splicing and Ca2+/NFAT signaling

S. Sengupta, K. O. West, S. Sanghvi, G. Laliotis, L. M. Agosto, K. W. Lynch, P. Tsichlis, H. Singh, K. L. Patrick, M. Guerau-de-Arellano

This study identifies PRMT5's role in modulating alternative splicing and Ca2+/NFAT signaling in activated T cells through symmetric dimethylation of RNA processing proteins.

ImmunoHorizons · Oct 29, 2021Peer-reviewedImmunology