Cancer BiologybioRxiv
The Endosomal pH Regulator NHE9 is a Driver of Stemness in Glioblastoma
M. Ko, M. R. Makena, P. V. Schiapparelli…·R. Rao
This paper identifies NHE9 as a driver of stemness in glioblastoma by showing it increases receptor tyrosine kinase stability and activates JAK2-STAT3 to induce pluripotency genes.
DOI 10.1093/pnasnexus/pgac013