Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes
R. Ruiz-Vega, C.-F. Chen, E. Razzak, P. Vasudeva, T. Krasieva, J. Shiu, M. G. Caldwell, H. Yan, J. Lowengrub, A. K. Ganesan, A. D. Lander
The paper investigates nevus growth arrest using a mouse model and finds that collective cell behavior, not cell-autonomous senescence, explains nevus size control.
bioRxiv · Jul 14, 2020Cancer Biology