Author

J. Lowengrub

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

H. Yan· 2 shared A. D. Lander· 1 shared A. K. Ganesan· 1 shared B. Chu· 1 shared C.-F. Chen· 1 shared D. Ramirez-Guerrero· 1 shared E. Razzak· 1 shared E. Read· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

H. Yan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stress generation, relaxation and size control in confined tumor growth

H. Yan, D. Ramirez-Guerrero, J. Lowengrub, M. Wu

This paper develops a continuum model to study how elastic stresses and active relaxation in tumors regulate growth and size under mechanical confinement and chemical gradients.

bioRxiv · Sep 1, 2021Biophysics

Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes

R. Ruiz-Vega, C.-F. Chen, E. Razzak, P. Vasudeva, T. Krasieva, J. Shiu, M. G. Caldwell, H. Yan, J. Lowengrub, A. K. Ganesan, A. D. Lander

The paper investigates nevus growth arrest using a mouse model and finds that collective cell behavior, not cell-autonomous senescence, explains nevus size control.

bioRxiv · Jul 14, 2020Cancer Biology

Hydrodynamics of transient cell-cell contact: The role of membrane permeability and active protrusion length

K. Liu, B. Chu, J. Newby, E. Read, J. Lowengrub, J. Allard

This paper simulates cell-cell contact formation to show that thin-layer fluid dynamics slow receptor-ligand interactions, requiring active forces or high permeability to overcome.

bioRxiv · Jul 12, 2018Biophysics