BiochemistrybioRxiv
Doxorubicin induces caspase-mediated proteolysis of KV7.1
A. Strigli, M. Schwake, C. Raab…·M. Luedde
This study identifies caspase-mediated proteolysis of Kv7.1 as a novel mechanism regulated by doxorubicin, leading to reduced cardiac potassium currents.
DOI 10.1038/s42003-018-0162-z