Author

P.-A. Nygren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Achour· 2 shared A. D. Duru· 1 shared A. M. Morro· 1 shared A. Olsson· 1 shared C. Madhurantakam· 1 shared E. B. Allerbring· 1 shared G. M. McInerney· 1 shared H. Uchtenhagen· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

A. Achour

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Author profile →

2 papers

Recent·Most cited

Caprin-1 binding to the critical stress granule protein G3BP1 is regulated by pH

T. Schulte, M. D. Panas, L. Wiliams, N. Kedersha, J. S. Fleck, T. J. C. Tan, A. Olsson, A. M. Morro, L. Hanke, J. Nilvebrant, K. A. Giang, P.-A. Nygren, P. Anderson, A. Achour, G. M. McInerney

This study shows that Caprin-1 binds to G3BP1's NTF2 domain with pH sensitivity, regulating stress granule formation through a SLiM-mediated mechanism.

bioRxiv · Feb 5, 2021Biochemistry

Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination

A. Achour, A. D. Duru, R. Sun, E. B. Allerbring, J. Chadderton, N. Kadri, X. Han, H. Uchtenhagen, C. Madhurantakam, S. Pellegrino, T. Sandalova, P.-A. Nygren, S. J. Turner

This paper shows that modifying peptides with proline can restore CD8 T-cell recognition of viral escape variants, enhancing vaccine effectiveness against immune evasion.

bioRxiv · Dec 2, 2019Immunology