Author

A. Achour

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:wet-lab / biochemical assay· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

N. Kadri· 3 shared P.-A. Nygren· 2 shared T. Sandalova· 2 shared A. C. Ko· 1 shared A. D. Duru· 1 shared A. K. Selvam· 1 shared A. K. Wagner· 1 shared A. Krstic· 1 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersImmunology

N. Kadri

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity

T. Amano, H. Yu, M. Amano, E. Leyder, M. Badiola, P. Ray, J. Kim, A. C. Ko, A. Achour, N.-p. Weng, E. Kochba, Y. Levin, M. S. H. Ko

This paper develops a temperature-controlled self-replicating RNA vaccine that elicits cellular immunity and can be used as a pan-coronavirus booster.

bioRxiv · Sep 5, 2022Immunology

PD-1 expression on NK cells can be related to cytokine stimulation and tissue residency

A. K. Wagner, N. Kadri, C. Tibbit, K. van de Ven, S. Bagawath-Singh, D. Oliinyk, E. LeGresly, N. Campbell, S. Trittel, P. Riese, T. Sandalova, A. Achour, K. Karre, B. J. Chambers

The paper investigates PD-1 expression on NK cells, showing its association with tumor-infiltrating NK cells and altered phenotypes in PD-1-deficient mice.

bioRxiv · Mar 29, 2021 · PreprintImmunology

Targeted enzyme assisted chemotherapy (TEAC) - a novel microRNA-guided and selenium-based regimen to specifically eradicate hepatocellular carcinoma

A. K. Selvam, M. Bjornstedt, R. Jawad, R. Gramignoli, A. Achour, H. Salter

This paper introduces a novel chemotherapy regimen using selenium and microRNA-guided induction of KYAT1 to specifically target hepatocellular carcinoma with reduced off-target effects.

bioRxiv · Feb 9, 2021 · PreprintCancer Biology

Caprin-1 binding to the critical stress granule protein G3BP1 is regulated by pH

T. Schulte, M. D. Panas, L. Wiliams, N. Kedersha, J. S. Fleck, T. J. C. Tan, A. Olsson, A. M. Morro, L. Hanke, J. Nilvebrant, K. A. Giang, P.-A. Nygren, P. Anderson, A. Achour, G. M. McInerney

This study shows that Caprin-1 binds to G3BP1's NTF2 domain with pH sensitivity, regulating stress granule formation through a SLiM-mediated mechanism.

bioRxiv · Feb 5, 2021Biochemistry

FOXO1 and FOXO3 cooperatively regulate innate lymphoid cell development

T. L. Thanh, J. Norskov, L. P. Perez, S. Kharazi, A. Krstic, S. Meinke, L. Schmied, N. Frengen, Y. Heshmati, M. Kierczak, T. Bouderlique, A. Wagner, C. Gustafsson, B. Chambers, A. Achour, , N. Kadri

This study identifies FOXO1 and FOXO3 as cooperative regulators of innate lymphoid cell development and maturation, affecting lineage specification and response to IL-15.

bioRxiv · Jan 13, 2021Cell Biology

Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination

A. Achour, A. D. Duru, R. Sun, E. B. Allerbring, J. Chadderton, N. Kadri, X. Han, H. Uchtenhagen, C. Madhurantakam, S. Pellegrino, T. Sandalova, P.-A. Nygren, S. J. Turner

This paper shows that modifying peptides with proline can restore CD8 T-cell recognition of viral escape variants, enhancing vaccine effectiveness against immune evasion.

bioRxiv · Dec 2, 2019Immunology