Molecular BiologybioRxivPreprint
Impaired ureagenesis due to arginine-insensitive N-acetylglutamate synthase
Parthasarathy Sonaimuthu, Emilee Senkevitch, Nantaporn Haskins…·Ljubica Caldovic
The paper investigates the role of L-arginine in NAGS activation and ureagenesis by studying NAGS knockout mice and a human patient with a related mutation.