Author

Patsy R Tomlinson

University of Cambridge

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Biology Disciplines

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Gemma V. BrierleyiD· 1 shared Helen C. SuiD· 1 shared Olga PerišićiD· 1 shared Rachel G. Knox· 1 shared Robert K. SempleiD· 1 shared Roger L WilliamsiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Gemma V. BrierleyORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivNov 2, 2023

Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant

Patsy R Tomlinson, Rachel G. Knox, Olga Perišić…·Robert K. Semple

The paper investigates an activating PIK3R1 variant linked to immunodeficiency and finds it acts as a dominant negative, reducing p110 signaling and explaining overlapping phenotypes.

3 citations

humanproteomics

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