NeurosciencebioRxivPreprint
The 5α-reductase inhibitor finasteride reduces opioid self-administration
Gabriel D. Bossé, Roberto Cadeddu, Gabriele Floris…·Randall Theodore Peterson
This study shows finasteride reduces opioid self-administration in zebrafish and rats without affecting locomotion or feeding, and suggests steroidogenic pathways as potential targets for OUD treatment.