BiophysicsbioRxivPreprint
Transient interdomain interactions shape the conformational ensemble governing RNA recognition by the tandem RRMs of Sex-lethal
Julia Meyer, Kristian Schweimer, Paul Matzner…·Janosch Hennig
This study shows that RNA recognition by the Sxl protein depends on a dynamic conformational ensemble rather than a single structure, and perturbing this balance impairs RNA binding.
DOI 10.64898/2026.08.06.743427