Cancer BiologyPLOS ONEPeer-reviewed
The role of oxygen in avascular tumor growth
David Robert Grimes, Pavitra Kannan, Alan McIntyre…·Mike Partridge
This study examines oxygen dynamics in tumor spheroids, showing that growth can be mechanistically modeled using cellular doubling time and oxygen consumption rate, validated with clinical measurements and treatment response.
DOI 10.1371/journal.pone.0153692