PhysiologybioRxivPreprint
Diabetic liver-enriched secretory dipeptidyl peptidase 4 (DPP4) fuels gut inflammation via attenuation of autophagy
Mohammad Athar, Ratulananda Bhadury, Chayanika Gogoi…·Devram Sampat Ghorpade
This study identifies liver-enriched DPP4 as a driver of gut inflammation in diabetes by inhibiting autophagy, leading to increased immune cell infiltration and colitis.