MicrobiologybioRxivPreprint
Phosphate-responsive ornithine lipid biosynthesis remodels outer membrane composition and contributes to polymyxin tolerance
Roberto Jhonatan Olea-Ozuna, Melanie J Campbell, Prithvijeet Singh Kharnal…·Joseph M Boll
This study identifies OlsF-dependent ornithine lipid biosynthesis as a phosphate-responsive pathway that remodels the outer membrane and enhances polymyxin tolerance in Enterobacterales.
DOI 10.64898/2026.11.03.764129