DHA deficiency drives neural oxidized-lipid stress and microglial activation
Ryo Hagimori, Purnima Gogoi, Pawan Kumar Shahi…·Akihiro Ikeda
This study shows that DHA deficiency causes lipid remodeling and microglial activation in mice, leading to oxidative stress and visual dysfunction, with APOE-dependent lipid disposal and galectin-3 involvement.