Chemoselective Bioconjugation Reveals Norepinephrinylation (NEylation) as a Widespread Post-Translational Modification in Cells
Lin Zeng, Xingyu Ma, Zhengjun Cai, Yunpeng Bai, Q Wang, Huapeng Li, Andrew Symasek, Adam R. Lovato, Sydny Lyon, Yin Zhao, Fei Gao, Nathaniel W. Mabe, Chongli Yuan, Zhong‐Yin Zhang, Qingfei Zheng
The paper develops a chemoselective bioconjugation method to detect and analyze NEylation, revealing it as a widespread PTM affecting protein function in cells.
bioRxiv · Aug 10, 2026 · PreprintBiochemistry