Author

Hong-Xuan Chen

Sun Yat-sen UniversityORCID 0009-0001-9385-6910Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:long-read sequencing· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Fu Wu· 2 shared Guan‐Zheng LuoiD· 2 shared Jin‐Wen Kong· 2 shared Ru‐Jia Luo· 2 shared Ye-Lin Lan· 2 shared Ying-Yuan XieiD· 2 shared Ze-Hui ReniD· 2 shared Zhang ZhangiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Fu Wu

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 10, 2026

Deciphering the epitranscriptomic code of RNA degradation with nanopore direct RNA sequencing

Zhang Zhang, Chen‐Long Wang, Zhihao Zhang…·Guan‐Zheng Luo

This study uses nanopore direct RNA sequencing to analyze how m6A modifications and poly(A) tail dynamics influence RNA degradation kinetics and isoform-specific decay.

DOI 10.64898/2026.05.09.723953

humanlong-read sequencing

𝕏 PostBluesky

BiochemistryNature CommunicationsPeer-reviewedJun 2, 2025

Single-Molecule Direct RNA Sequencing Reveals the Shaping of Epitranscriptome Across Multiple Species

Ying-Yuan Xie, Zhen-Dong Zhong, Hong-Xuan Chen…·Guan‐Zheng Luo

This study introduces SingleMod, a deep learning model for m6A modification mapping using single-molecule RNA sequencing, revealing m6A heterogeneity and species-specific distribution patterns.

51 citationstop 1%

humanlong-read sequencing

𝕏 PostBluesky