Transcriptional heterogeneity in diabetic foot wounds
T. Sandoval-Schaefer, Q. Phan, B. Dash, A. Prassinos, K. Duan, M. I. Gazes, S. D. Vyce, H. C. Hsai, R. Driskell, V. Horsley
This study uses single-cell RNA sequencing to identify transcriptional changes in diabetic foot ulcers compared to non-diabetic wounds, revealing defects in keratinocyte differentiation, fibroblast function, and macrophage metabolism.
bioRxiv · Feb 16, 2023 · PreprintCell Biology