Author

A. P. Mitchell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:mouse· 6 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

N. V. Solis· 5 shared S. G. Filler· 5 shared J. Lin· 4 shared H. Liu· 3 shared M. Swidergall· 3 shared Q. T. Phan· 3 shared D. J. Krysan· 2 shared M. Wellington· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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5 shared papersMicrobiology

N. V. Solis

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Candida albicans stimulates the formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection

Q. T. Phan, N. V. Solis, M. V. Cravener, M. Swidergall, J. Lin, M. Y. Huang, H. Liu, S. Singh, A. S. Ibrahim, M. Mazzone, A. P. Mitchell, S. G. Filler

This study identifies a multi-receptor complex involving c-Met, E-cadherin, and EGFR that C. albicans uses to invade oral epithelial cells, with Hyr1 and Als3 facilitating this process and dual inhibition of c-Met and EGFR reducing virulence.

bioRxiv · Feb 23, 2023 · PreprintMicrobiology

Identification of Serum Bridging Molecules that Mediate Human Endothelial Cell Invasion by Candida species

Q. T. Phan, N. V. Solis, J. Lin, M. Swidergall, S. Singh, H. Liu, D. Sheppard, A. Ibrahim, A. P. Mitchell, S. G. Filler

This paper identifies serum proteins that mediate endothelial cell invasion by non-C. albicans Candida species through bridging molecule-mediated endocytosis.

bioRxiv · Sep 18, 2021 · PreprintMicrobiology

In vivo complex haploinsufficiency-based genetic analysis identifies a transcription factor circuit regulating Candida albicans oropharyngeal infection and epithelial cell endocytosis

N. V. Solis, R. S. Wakade, T. L. Ollinger, M. Wellington, A. P. Mitchell, S. G. Filler, D. J. Krysan

The paper identifies a transcription factor circuit regulating C. albicans oropharyngeal infection and epithelial cell endocytosis through genetic interaction analysis in a mouse model.

bioRxiv · May 24, 2021 · PreprintMicrobiology

Intravital imaging of Candida albicans identifies differential in vitro and in vivo filamentation phenotypes for transcription factor deletion mutants

D. J. Krysan, R. S. Wakade, m. huang, A. P. Mitchell, M. Wellington

This paper uses intravital imaging to compare in vitro and in vivo filamentation phenotypes of C. albicans transcription factor mutants, finding distinct regulatory patterns in vivo.

bioRxiv · May 10, 2021Microbiology

Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung

H. Liu, W. Xu, V. M. Bruno, Q. T. Phan, N. V. Solis, C. A. Woolford, R. Ehrlich, A. C. Shetty, C. McCracken, J. Lin, A. P. Mitchell, S. G. Filler

The paper identifies two transcription factors, RlmA and Ace1, critical for Aspergillus fumigatus virulence by analyzing gene expression during lung infection in mice.

bioRxiv · Dec 23, 2020Microbiology

Activation of oral epithelial EphA2-EFGR signaling by Candida albicans virulence factors

M. Swidergall, N. V. Solis, N. Millet, M. Y. Huang, J. Lin, Q. Phan, M. D. Lazarus, Z. Wang, A. P. Mitchell, S. G. Filler

This study investigates how Candida albicans virulence factors Als3 and Ece1/Candidalysin interact with host receptors EphA2 and EGFR to induce inflammation during oropharyngeal candidiasis.

bioRxiv · May 7, 2020 · PreprintMicrobiology

Function of BriC Peptide in the Pneumococcal Competence and Virulence Portfolio

S. D. Aggarwal, R. Eutsey, J. West-Roberts, A. Domenech, W. Xu, I. T. Abdullah, A. P. Mitchell, J.-W. Veening, H. Yesilkaya, N. L. Hiller

This study identifies BriC as a competence-induced gene in Streptococcus pneumoniae that promotes biofilm development and colonization, with its expression regulated by the ComE master regulator and showing genomic plasticity in some isolates.

bioRxiv · Jul 10, 2018Microbiology