Author

Qian Liang

Army Medical UniversityPrimary ORCID profile (0009-0001-9657-0280 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Qian LiangiD1 paper

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Anneliese O. SpeakiD· 1 shared Brian M. OrtmanniD· 1 shared Dan Cai· 1 shared E GuojiiD· 1 shared Erlong ZhangiD· 1 shared Gang XuiD· 1 shared Guibo LiiD· 1 shared Hongyu Xue· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Anneliese O. SpeakORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedMar 12, 2026

VHL synthetic lethality screens uncover CBF-beta as a negative regulator of STING

James A.C. Bertlin, Tekle Pauzaite, Qian Liang…·James A. Nathan

The paper identifies CBF-beta as a negative regulator of STING through synthetic lethality screens in VHL-null ccRCC cells, showing its role in type I interferon signaling and tumor growth.

4 citationstop 3%

humanCRISPR screen

𝕏 PostBluesky

Cancer BiologybioRxivPreprintAug 15, 2025

Hypobaric hypoxia drives citrate cycle reprogramming to suppress tumor progression

Yixing Gao, Xiuju He, E Guoji…·Erlong Zhang

This study shows hypobaric hypoxia suppresses tumor progression by reprogramming the citrate cycle and inhibiting the HIF-1 pathway, enhancing antitumor immune response and improving therapy outcomes.

DOI 10.1101/2025.08.15.669572

𝕏 PostBluesky