Author

Qian Qu

Shanghai Jiao Tong University

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Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:yeast· 1

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Huasong AiiD· 1 shared Lei LiuiD· 1 shared Maoshen SuniD· 1 shared Xiangwei WuiD· 1 shared Yunxiang DuiD· 1 shared Zhengqing LiiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperMolecular Biology

Huasong AiORCID

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1 paper

Recent·Most cited

Molecular BiologyScience AdvancesPeer-reviewedMay 30, 2025

Mechanistic Insights into the Stimulation of the Histone H3K9 Methyltransferase Clr4 by Proximal H3K14 Ubiquitination

Yunxiang Du, Maoshen Sun, Zhengqing Li…·Lei Liu

The paper determines the crystal structures of Clr4 bound to ubiquitinated and unmodified H3 peptides, revealing how H3K14 ubiquitination synergistically enhances Clr4 catalytic activity through conformational changes and multivalent interactions.

11 citations

yeastexperimental assay

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