Qian Xu

The paper introduces BioSecBench-Function, a benchmark for assessing AI agents' ability to infer biological function from experimental data, showing varying performance across models and tasks.

This study identifies PP2A inactivation as a key driver of myocardial injury in TTS, showing that restoring PP2A or inhibiting JNK reduces ferroptosis and mitochondrial dysfunction.

The paper shows that host-derived extracellular vesicles promote malaria parasite development in mosquitoes by reprogramming lipid metabolism through fatty acid oxidation.

This study investigates the role of RSPO3 in estrogen-mediated sex differences in body fat distribution using single-cell RNA sequencing and spatial transcriptomics in humans and mice.

The paper introduces CrossmodalNet, an interpretable model that predicts surface protein expression from scRNA-seq data and incorporates temporal information to uncover gene-protein relationships.

scTenifoldKnk predicts gene function via virtual knockout using scRNA-seq data from wild-type samples, recapitulating real-animal KO results.