Selective activation of IRE-1 safeguards restoration of translation and organismal rejuvenation from adult reproductive diapause
Qiang Fan, Ao Guo, 王淑娟…·Meng‐Qiu Dong
This study shows that refeeding reverses aging-like phenotypes in C. elegans reproductive diapause by selectively activating the IRE-1 branch of UPRER and enhancing protein synthesis and folding.