GeneticsbioRxivPreprint
In vivo-directed evolution identifies AAV-WM04 as a next-generation vector for potent and durable hearing restoration in DFNB9
Yong Kang Tao, Cenfeng Chu, Zhenzhe Cheng…·Hao Wu
This study identifies AAV-WM04 as a highly efficient and safe gene delivery vector for targeting inner hair cells in the cochlea, showing effectiveness in mice and non-human primates for treating hereditary hearing loss.
DOI 10.64898/2026.03.11.710960