Cell BiologybioRxivPreprint
Coronary Artery Disease Transcriptomics Reveals Two Drivers of the Endothelial Cell SR-BI Expression and LDL Transport that Underlie Atherosclerosis
Linzhang Huang, Yibin Huang, Jiayu Zhu…·Philip W. Shaul
This study identifies two factors, hypercholesterolemia and disturbed blood flow, that upregulate endothelial SR-BI to drive LDL transport and atherosclerosis.