Author

Rémi Opsomer

UCLouvain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Pascal Kienlen‐CampardiD· 3 shared Bernadette Tasiaux· 2 shared Céline VrancxiD· 2 shared Florian PerriniD· 2 shared Jean‐Noël Octave· 2 shared Anna Doshina· 1 shared Caroline Evrard· 1 shared Devkee M. VadukuliD· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Pascal Kienlen‐CampardORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceiSciencePeer-reviewedDec 1, 2020

Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization

Florian Perrin, Nicolas Papadopoulos, Núria Suelves…·Stefan N. Constantinescu

The paper shows that dimeric orientations of C99 influence γ-secretase cleavage lines, affecting Aβ42 processing and gene transcription.

20 citations

humanexperimental assay

𝕏 PostBluesky

NeuroscienceeNeuroPeer-reviewedApr 23, 2020

Amyloid Precursor Protein (APP) controls excitatory/inhibitory synaptic inputs by regulating the transcriptional activator Neuronal PAS Domain Protein 4 (NPAS4)

Rémi Opsomer, Sabrina Contino, Florian Perrin…·Pascal Kienlen‐Campard

This study identifies NPAS4 as a target of APP regulation, showing APP controls excitatory/inhibitory synaptic inputs by modulating NPAS4 expression in neurons.

34 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceFrontiers in Cellular NeurosciencePeer-reviewedNov 22, 2018

Contribution of the endosomal-lysosomal and proteasomal systems in Amyloid-β Precursor Protein derived fragments processing

Caroline Evrard, Pascal Kienlen‐Campard, Mathilde Coevoet…·Valérie Vingtdeux

This study investigates the roles of endosomal-lysosomal and proteasomal pathways in processing APP-derived fragments, showing distinct degradation mechanisms for full-length APP and overexpressed C99.

36 citations

humanproteomics

𝕏 PostBluesky