Author

R. A. Lawrenson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. E. Pease· 2 shared S. Sriskandan· 2 shared A. Fosberry· 1 shared C. Haslam· 1 shared D. Mossakowska· 1 shared E. J. Jones· 1 shared J. C. Brown· 1 shared J. Goldblatt· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

J. E. Pease

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MicrobiologybioRxivPreprintNov 14, 2021

Structure-activity studies of Streptococcus pyogenes enzyme SpyCEP reveal high affinity for CXCL8 in the SpyCEP C-terminal

M. Pearson, C. Haslam, A. Fosberry…·S. Sriskandan

This study investigates SpyCEP's enzymatic function, revealing the C-terminal's role in substrate binding and the N-terminal's necessity for full catalytic activity.

DOI 10.1101/2021.11.14.468564

proteomicsexperimental assay

𝕏 PostBluesky

ImmunologybioRxivDec 18, 2018

A requirement for neutrophil glycosaminoglycans in chemokine:receptor interactions is revealed by the streptococcal protease SpyCEP

J. Goldblatt, R. A. Lawrenson, L. Muir…·J. E. Pease

This study shows that SpyCEP cleavage of CXCL8 impairs chemokine-receptor interactions by disrupting glycosaminoglycan binding, affecting neutrophil migration.

DOI 10.4049/jimmunol.1801688

humanproteomics

𝕏 PostBluesky