MicrobiologybioRxiv
Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins
F. Zhang, T. Zang, E. M. Stevenson…·P. D. Bieniasz
This study identifies ORF7a proteins from sarbecoviruses as inhibitors of MHC-I antigen presentation, with a single amino acid difference affecting their function.
DOI 10.1073/pnas.2209042119