Author

R. B. Sim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

U. Kishore· 2 shared A. Al Aiyan· 1 shared C. Kumar· 1 shared H. A. Khan· 1 shared K. Pondman· 1 shared M. Mayora Neto· 1 shared N. Beirag· 1 shared N. J. Temperton· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

U. Kishore

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2 papers

Recent·Most cited

The human complement factor B-C3b complex: Investigation of the interaction using C3b bound to thiol-Sepharose

S. Williams, K. Pondman, P. Varghese, A. Al Aiyan, U. Kishore, R. B. Sim

This study investigates the interaction between factor B and C3b using competition assays, finding that specific antibodies can inhibit or enhance complex formation.

bioRxiv · Jan 16, 2024 · PreprintImmunology

Human complement Factor H and Properdin act as soluble pattern recognition receptors and differentially modulate SARS-CoV-2 Infection

N. Beirag, P. M. Varghese, C. Kumar, S. Idicula-Thomas, M. Mayora Neto, H. A. Khan, R. B. Sim, T. Madan, N. J. Temperton, U. Kishore

This study shows that complement factors FH and FP interact with SARS-CoV-2 proteins and differentially modulate viral entry and inflammatory responses in A549 cells.

bioRxiv · Jul 7, 2023 · PreprintImmunology