N. J. Temperton

This study maps the interaction sites between Influenza A viruses and human complement Factor H, showing strain-specific effects on viral entry and replication.

This study shows that complement factors FH and FP interact with SARS-CoV-2 proteins and differentially modulate viral entry and inflammatory responses in A549 cells.

The study detects neutralizing antibodies against henipavirus, Nipah virus, and bat influenza in Eidolon helvum bats in Nigeria, suggesting a potential zoonotic spillover risk.

This study evaluates electrostatic precipitation as a method to capture and inactivate viral particles in bioaerosols during laparoscopic surgery, showing effectiveness against both enveloped and non-enveloped viruses.

This study shows that rfhSP-D enhances SARS-CoV-2 Spike protein binding to DC-SIGN and increases viral uptake in DC-SIGN-expressing cells while reducing inflammation.

This study compares lyophilisation protocols for filovirus pseudotypes, finding that proper lyophilisation maintains stability and functionality for neutralisation assays even at high temperatures.

The paper develops NA pseudotype vectors and a pELLA assay to measure neuraminidase inhibition, showing improved sensitivity over existing methods for vaccine immunogenicity assessment.

The paper develops HA pseudotype libraries for Influenza A and B to improve vaccine antigen selection and neutralization assay capabilities.

This study shows that hyperimmune chicken reference sera are not suitable for validating influenza pseudotype neutralization assays due to unexplained cross-reactivity.