R. C. Edgar

The paper identifies a new class of viroid-like elements, Obelisks, prevalent in human microbiomes and capable of persistent colonization.

This paper identifies MMV1557817 as a dual aminopeptidase inhibitor effective against multiple Plasmodium species and highlights its potential as a multi-target antimalarial drug.

The paper identifies ambiviruses as viroid-like elements with rolling circle replication and their own viral RdRP, suggesting a hybrid evolutionary origin between RNA viruses and sub-viral elements.

The paper challenges claims of discovering new RNA virus phyla in Tara Oceans data, showing most sequences belong to known phyla and questioning the validity of the new phyla claims.

This paper demonstrates a technology to capture and recreate diverse antibody repertoires as multivalent recombinant drugs, showing applications against SARS-CoV-2, Zika virus, and graft-versus-host disease.

The paper evaluates taxonomy annotation errors in 16S rRNA databases, finding ~15% error rates in SILVA and Greengenes and ~10% in RDP.