Author

R. E. Aparicio

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

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D. W. Sirkis· 1 shared R. Schekman· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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1 shared paperCell Biology

D. W. Sirkis

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1 paper

Recent·Most cited

Cell BiologybioRxivJun 23, 2017

Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER-Golgi intermediate compartment

D. W. Sirkis, R. E. Aparicio, R. Schekman

This study shows that neurodegeneration-associated TREM2 mutants fail to mature and reach the cell surface, accumulating in the ERGIC and suggesting its role in quality control.

DOI 10.1091/mbc.e17-06-0423

humanproteomics

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