An integrated strategy reveals complex glycosylation of erythropoietin using top-down and bottom-up mass spectrometry
Y. Guan, M. Zhang, M. Gaikwad, H. Voss, R. Fazel, S. Ansari, H. Shen, J. Wang, S. Hartmut
This paper develops an integrated mass spectrometry strategy to analyze the complex glycosylation of erythropoietin, identifying N- and O-glycan structures and their site-specific modifications.
bioRxiv · Feb 9, 2021Biochemistry