S. Ansari

Quantifying yeast microtubules and spindles using the Toolkit for Automated Microtubule Tracking (TAMiT)

The paper introduces TAMiT, an automated tool for tracking fluorescent microtubules in yeast cells, showing it reliably detects and measures microtubule dynamics even at low signal-to-noise ratios.

Towards development of serum substitute medium to induce osteoclast differentiation of human peripheral blood derived monocytes

This paper develops a serum substitute medium to support osteoclast differentiation from human peripheral blood monocytes, achieving all functional markers after 21 days of culture.

Matrix vesicle isolation from a three-dimensional in vitro bone model

This study isolates and characterizes matrix vesicles from a 3D in vitro bone model, showing they resemble natural matrix vesicles and could be used for bone regeneration.

Development of serum substitute medium for bone tissue engineering

This study develops a serum substitute medium for bone tissue engineering that performs as well as fetal bovine serum in cell attachment, survival, and matrix deposition under mechanical stress.

Human endogenous retrovirus-R envelope is a host restriction factor against severe acute respiratory syndrome-coronavirus-2

The paper identifies HERV-R envelope as a host restriction factor that inhibits SARS-CoV-2 replication through ERK and p38 MAPK signaling.

Kinesin-5/Cut7 moves bidirectionally on fission-yeast spindles with activity that increases in anaphase

This study shows that the kinesin-5 motor Cut7p moves bidirectionally on fission yeast spindles, with increased activity during anaphase B, and its localization is dependent on its motility.

Alkaline phosphatase activity of serum affects osteogenic differentiation cultures

This study shows that alkaline phosphatase activity in fetal bovine serum affects mineral deposition and osteogenic differentiation in cell cultures.

Recombinant binder of sperm protein1 (rec-BSP1) as a potent fertility factor mediates its effect on embryo production

This study optimizes the production of rec-BSP1 and demonstrates its ability to enhance buffalo sperm motility and blastocyst production in vitro.

An integrated strategy reveals complex glycosylation of erythropoietin using top-down and bottom-up mass spectrometry

This paper develops an integrated mass spectrometry strategy to analyze the complex glycosylation of erythropoietin, identifying N- and O-glycan structures and their site-specific modifications.

A newly identified prophage-encoded gene, ymfM, causes SOS-inducible filamentation in Escherichia coli

This study identifies ymfM, a prophage-encoded gene, as an SOS-inducible cell division inhibitor in E. coli that causes filamentation independently of SulA.

An Organoid for woven Bone

This study develops a 3D in vitro organoid model of woven bone formation using human bone marrow stromal cells, demonstrating osteoblast and osteocyte co-culture and mineralization.

Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

This study develops a computational model of fission-yeast mitosis to analyze mechanisms of chromosome biorientation and bipolar spindle assembly.