Actuation Enhances Patterning in Human Neural Tube Organoids
A. R. A. Fattah, B. Daza, G. Rustandi, M. A. Berrocal-Rubio, B. Gorissen, S. Poovathingal, K. Davie, X. Cao, D. H. Rosenzweig, Y. Lei, R. Finnell, C. Verfaillie, M. Sampaolesi, P. Dedecker, H. Van Oosterwyck, , A. Ranga
The paper shows that applying active mechanical forces to human neural tube organoids enhances their patterning and growth through temporally restricted mechanoregulation.
bioRxiv · Sep 22, 2020Bioengineering