Cell BiologybioRxiv
Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetes patients
J. Farup, J. Just, F. de Paoli…·N. Jessen
This study identifies CD90+ fibro-adipogenic progenitors in T2DM skeletal muscle and shows PDGF signaling drives their pathogenic behavior, which is mitigated by Metformin.
DOI 10.1016/j.cmet.2021.10.001