ImmunologybioRxiv
Altered basal lipid metabolism underlies the functional impairment of naive CD8+ T cells in elderly humans
F. Nicoli, M. Cabral-Piccin, L. Papagno…·V. Appay
This study identifies age-related alterations in basal lipid metabolism of naive CD8+ T cells in elderly humans, which impair their function and can be partially reversed with lipid-altering drugs.
DOI 10.4049/jimmunol.2100194